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2.
Curr Psychol ; : 1-12, 2022 Dec 02.
Artigo em Inglês | MEDLINE | ID: covidwho-2236797

RESUMO

While an expanding body of research has revealed the beneficial impacts of visionary leadership on employees' work-related outcomes, little is known about its spillover effects on nonwork domains. Drawing upon work-home resources theory, we investigated the impacts of visionary leadership on employees' work-to-family conflict (WFC). Utilizing three-wave data from 268 employees, the results indicate that visionary leadership promotes follower relational energy, which in turn reduces WFC. Furthermore, perceived COVID-19 crisis disruption was found to strengthen the negative indirect link between visionary leadership and employees' WFC. Our research broadens our understanding of the potential positive spillover effects of visionary leadership in the nonwork domain through relational energy, and the accentuating effect of perceived crisis disruption on the work-family interface. The theoretical and managerial implications of these findings are discussed.

3.
Current psychology (New Brunswick, NJ) ; : 1-12, 2022.
Artigo em Inglês | EuropePMC | ID: covidwho-2147763

RESUMO

While an expanding body of research has revealed the beneficial impacts of visionary leadership on employees’ work-related outcomes, little is known about its spillover effects on nonwork domains. Drawing upon work–home resources theory, we investigated the impacts of visionary leadership on employees’ work-to-family conflict (WFC). Utilizing three-wave data from 268 employees, the results indicate that visionary leadership promotes follower relational energy, which in turn reduces WFC. Furthermore, perceived COVID-19 crisis disruption was found to strengthen the negative indirect link between visionary leadership and employees’ WFC. Our research broadens our understanding of the potential positive spillover effects of visionary leadership in the nonwork domain through relational energy, and the accentuating effect of perceived crisis disruption on the work–family interface. The theoretical and managerial implications of these findings are discussed.

4.
Nat Microbiol ; 7(8): 1259-1269, 2022 08.
Artigo em Inglês | MEDLINE | ID: covidwho-1972611

RESUMO

Pangolins are the most trafficked wild animal in the world according to the World Wildlife Fund. The discovery of SARS-CoV-2-related coronaviruses in Malayan pangolins has piqued interest in the viromes of these wild, scaly-skinned mammals. We sequenced the viromes of 161 pangolins that were smuggled into China and assembled 28 vertebrate-associated viruses, 21 of which have not been previously reported in vertebrates. We named 16 members of Hunnivirus, Pestivirus and Copiparvovirus pangolin-associated viruses. We report that the L-protein has been lost from all hunniviruses identified in pangolins. Sequences of four human-associated viruses were detected in pangolin viromes, including respiratory syncytial virus, Orthopneumovirus, Rotavirus A and Mammalian orthoreovirus. The genomic sequences of five mammal-associated and three tick-associated viruses were also present. Notably, a coronavirus related to HKU4-CoV, which was originally found in bats, was identified. The presence of these viruses in smuggled pangolins identifies these mammals as a potential source of emergent pathogenic viruses.


Assuntos
COVID-19 , Quirópteros , Animais , Humanos , Mamíferos , Pangolins , SARS-CoV-2/genética
5.
World J Clin Cases ; 10(8): 2457-2467, 2022 Mar 16.
Artigo em Inglês | MEDLINE | ID: covidwho-1771817

RESUMO

BACKGROUND: Coronavirus disease 2019 (COVID-19) has become a worldwide pandemic and significant public health issue. The effectiveness of extracorporeal membrane oxygenation (ECMO) in treating COVID-19 patients has been called into question. AIM: To conduct a meta-analysis on the mortality of COVID-19 patients who require ECMO. METHODS: This analysis adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes 2020 (PRISMA) and has been registered at the International Prospective Register of Systematic Reviews (number CRD42020227414). A quality assessment for all the included articles was performed by the Newcastle-Ottawa Scale (NOS). Studies with tenor more COVID-19 patients undergoing ECMO were included. The random-effects model was used to obtain the pooled incidence of mortality in COVID-19 patients receiving ECMO. The source of heterogeneity was investigated using subgroup and sensitivity analyses. RESULTS: We identified 18 articles with 1494 COVID-19 patients who were receiving ECMO. The score of the quality assessment ranged from 5 to 8 on the NOS. The majority of patients received veno-venous ECMO (93.7%). Overall mortality was estimated to be 0.31 [95% confidence interval (CI): 0.24-0.39; I 2 = 84.8%] based on random-effect pooled estimates. There were significant differences in mortality between location groups (33.0% vs 55.0% vs 37.0% vs 18.0%, P < 0.001), setting groups (28.0% vs 34.0%, P < 0.001), sample size (37.0% vs 31.0%, P < 0.001), and NOS groups (39.0% vs 19.0%, P < 0.001). However, both subgroup analyses based on location, setting, and sample size, and sensitivity analysis failed to identify the source of heterogeneity. The funnel plot indicated no evident asymmetry, and the Egger's (P = 0.95) and Begg's (P = 0.14) tests also revealed no significant publication bias. CONCLUSION: With more resource assessment and risk-benefit analysis, our data reveal that ECMO might be a feasible and effective treatment for COVID-19 patients.

6.
J Diabetes Investig ; 13(1): 148-155, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: covidwho-1621938

RESUMO

AIMS/INTRODUCTION: To explore the relationship between handgrip strength per weight (HGS/W), triglyceride glucose index (TyG) and diabetes, and whether lower HGS levels precede TyG in the Chinese elderly population. MATERIALS AND METHODS: Two linear regression models were used to explore the association of whether baseline HGS/W predicted follow-up variation of TyG or baseline TyG predicted follow-up variation of HGS/W. The logistic regression model was used to examine the relationship between baseline HGS/W and future diabetes. RESULTS: A total of 4,561 participants in the China Health and Retirement Longitudinal Study were enrolled, of which 47.0% were men, and the mean age was 58.7 years (standard deviation 8.68 years). A lower baseline HGS/W significantly correlated with a higher level of follow-up TyG (ß = -0.173, P = 0.002). The baseline level of HGS/W was significantly negatively associated with the incidence risk of diabetes (rate ratio 0.375, P = 0.004). However, in sex stratification, the statistical association between HGS/W and TyG and diabetes was only in men. CONCLUSIONS: Our results showed that HGS/W was inversely associated with TyG and diabetes, and lower HGS/W levels preceded TyG levels in the elderly population. However, the effect was inconsistent between men and women, and the possible mechanism would require further clarification.


Assuntos
Glicemia/análise , Diabetes Mellitus Tipo 2/etiologia , Força da Mão , Fatores Sexuais , Triglicerídeos/sangue , Idoso , Povo Asiático/estatística & dados numéricos , Peso Corporal , China/epidemiologia , Diabetes Mellitus Tipo 2/epidemiologia , Feminino , Humanos , Incidência , Modelos Lineares , Modelos Logísticos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Medição de Risco , Fatores de Risco
7.
Annu Int Conf IEEE Eng Med Biol Soc ; 2021: 4757-4760, 2021 11.
Artigo em Inglês | MEDLINE | ID: covidwho-1566233

RESUMO

The COVID-19 outbreak has caused the mortality worldwide and the use of swab sampling is a common way of screening and diagnosis. To combat respiratory infectious diseases and assist sampling, robots have been utilized and shown promising potentials. Nonetheless, a safe, patient-friendly, and low-cost swabbing system would be crucial for the practical implementation of robots in hospitals or inspection stations. In this study, we proposed two recyclable and cost-efficient end-effector designs that can be equipped at the distal end of a robot to passively regulate or actively sense the force exerted onto patients. One way is to introduce passive compliant mechanisms with soft material to increase the flexibility of the swabbing system, while the other way is utilizing a force-sensing gripper with embedded optoelectronic sensors to actively sense the force or torque. The proposed designs were modelled computationally and tested experimentally. It is identified that the passive compliant mechanisms can increase the flexibility of the swabbing system when subjected to the lateral force and mitigate the vertical force resulted from buckling. The lateral force range that the force-sensing gripper can detect is 0-0.35 N and the vertical force range causing buckling effect that can be sensed by gripper is 1.5-2.5 N.


Assuntos
COVID-19 , Doenças Transmissíveis , Robótica , Doenças Transmissíveis/diagnóstico , Humanos , SARS-CoV-2
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